Title : Grapefruit component interacting with rat and human P450 CYP3A: possible involvement of non-flavonoid components in drug interaction.

Pub. Date : 1997 May

PMID : 9178939






1 Functional Relationships(s)
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1 CYP3A-catalyzed 6beta-hydroxylation of testosterone in livers of rat and human was inhibited by the addition of an ethyl acetate-extract of grapefruit juice. Testosterone cytochrome P450, family 3, subfamily a, polypeptide 62 Rattus norvegicus