Title : Differential regulation of TNF alpha, IL-1 beta, IL-6, IL-8, TNF beta, and IL-10 by pentoxifylline.

Pub. Date : 1996 Dec

PMID : 9172017






4 Functional Relationships(s)
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1 Differential regulation of TNF alpha, IL-1 beta, IL-6, IL-8, TNF beta, and IL-10 by pentoxifylline. Pentoxifylline interleukin 6 Homo sapiens
2 We investigated PTX effects on production and mRNA expression of TNF alpha, IL-1 beta, IL-6, IL-8, TNF beta and IL-10. Pentoxifylline interleukin 6 Homo sapiens
3 Moreover, we observed that depending on the way of activating cells, PTX induced an up- or a down-regulation (in PMA + PHA or LPS stimulated cells, respectively) for IL-1 and IL-6 release. Pentoxifylline interleukin 6 Homo sapiens
4 We also noted that the effects of PTX on IL-6, IL-8 and IL-10 production were different in WB and in PBMC culture. Pentoxifylline interleukin 6 Homo sapiens