Title : In vitro activation of the human Harvey-ras proto-oncogene by aflatoxin B1.

Pub. Date : 1997 May

PMID : 9163674






1 Functional Relationships(s)
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1 It appears that, in contrast to the frequently reported G-->T transversions in codon 249 of the p53 gene in primary hepatomas in aflatoxin-exposed humans, the failure to detect Ha-ras mutations in these tumours is not due to an inability of aflatoxin B1 to activate this proto-oncogene. Aflatoxins tumor protein p53 Homo sapiens