Pub. Date : 1997 May 16
PMID : 9148913
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Unlike other tested phospholipids, phosphatidylinositol 4,5-bisphosphate, which binds to several PH domains, competed with PKC for binding to the PH domain apparently because their binding sites on the amino-terminal portion of the PH domains overlap. | Phosphatidylinositol 4,5-Diphosphate | proline rich transmembrane protein 2 | Homo sapiens |
2 | These results indicate that PKC binding to PH domains involve the beta2-beta3 region of the Btk PH domain and the C1 region of PKC, and agents that interact with either of these regions (i.e. phosphatidylinositol 4,5-bisphosphate binding to the PH domain and PMA binding to the C1 region of PKC) might act to regulate PKC-PH domain binding. | Phosphatidylinositol 4,5-Diphosphate | proline rich transmembrane protein 2 | Homo sapiens |