Title : The role of angiotensin II in the feedback control of renin gene expression.

Pub. Date : 1997 Jun

PMID : 9136670






2 Functional Relationships(s)
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1 To this end the renin system in male Sprague Dawley rats was stimulated by unilateral renal artery clipping (0.2 mm clip), by furosemide (60 mg/kg per diem) or isoproterenol (160 microg/kg per diem), and by ingestion of a low-salt diet (0.02%), or was suppressed by setting a contralateral renal artery clip (0.2-mm clip) or by ingestion of a high-salt diet (4%). Furosemide renin Rattus norvegicus
2 Renin gene expression was stimulated four- to fivefold by renal artery clipping and isoproterenol infusion, two- to three-fold by furosemide and a low-salt diet, and about four-fold by losartan. Furosemide renin Rattus norvegicus