Title : Determination of montelukast (MK-0476) and its S-enantiomer in human plasma by stereoselective high-performance liquid chromatography with column-switching.

Pub. Date : 1997 Feb

PMID : 9127275






1 Functional Relationships(s)
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1 A steoreoselective high-performance liquid chromatographic method was developed for the quantification of montelukast (free acid of Singulair, or MK-0476), a potent and selective leukotriene D4 (cysLT1) receptor antagonist, and it S-enantiomers (L-768,232). Leukotriene D4 cysteinyl leukotriene receptor 1 Homo sapiens