Pub. Date : 1996 Dec 2
PMID : 9117410
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Depending on experimental conditions, chronic cocaine exposure can induce an increase in binding to the dopamine transporter (DAT). | Cocaine | solute carrier family 6 member 3 | Rattus norvegicus |
| 2 | Depending on experimental conditions, chronic cocaine exposure can induce an increase in binding to the dopamine transporter (DAT). | Cocaine | solute carrier family 6 member 3 | Rattus norvegicus |
| 3 | One possible mechanism for the cocaine-induced-upregulation in DAT binding sites is through stimulation of presynaptic D2 receptors by excess synaptic dopamine. | Cocaine | solute carrier family 6 member 3 | Rattus norvegicus |
| 4 | Striatal DAT binding was then examined autoradiographically using the DAT-selective cocaine congeners [125I]RTI-121 and [3H]WIN 35428. | Cocaine | solute carrier family 6 member 3 | Rattus norvegicus |