Title : Expression of NFAT-family proteins in normal human T cells.

Pub. Date : 1997 May

PMID : 9111316






2 Functional Relationships(s)
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1 Using a panel of specific antisera in immunoprecipitation assays, we found that NFATp (135 kDa) is constitutively expressed in normal human T cells, while synthesis of NFATc (predominant form of 86 kDa) is induced by ionomycin treatment. Ionomycin nuclear factor of activated T cells 2 Homo sapiens
2 Surprisingly, the PMA-ionomycin-induced synthesis of NFATc that was detected by immunoprecipitation was not mirrored in the DNA binding assays: nearly all of the activity was due to NFATp. Ionomycin nuclear factor of activated T cells 2 Homo sapiens