Title : Distinction of CYP1A1 and CYP1A2 activity by selective inhibition using fluvoxamine and isosafrole.

Pub. Date : 1997 Feb 21

PMID : 9105404






2 Functional Relationships(s)
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1 Distinction of CYP1A1 and CYP1A2 activity by selective inhibition using fluvoxamine and isosafrole. Fluvoxamine cytochrome P450 family 1 subfamily A member 2 Homo sapiens
2 Isosafrole and fluvoxamine were found to inhibit CYP1A2 selectively, with Ki values of 14 and 800 times, respectively, lower than those for CY1A1. Fluvoxamine cytochrome P450 family 1 subfamily A member 2 Homo sapiens