Pub. Date : 1997 Feb 21
PMID : 9105396
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Acquisition of taxol resistance via P-glycoprotein- and non-P-glycoprotein-mediated mechanisms in human ovarian carcinoma cells. | Paclitaxel | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Acquisition of taxol resistance via P-glycoprotein- and non-P-glycoprotein-mediated mechanisms in human ovarian carcinoma cells. | Paclitaxel | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | In contrast, the 2008/13 clones followed the classical P-glycoprotein-mediated resistance phenotype until a 245-fold taxol-resistant clone (2008/13/2) was obtained, which was followed by a further increase in the degree of resistance but significant down-regulation of P-glycoprotein expression in the 252-fold taxol-resistant 2008/13/4 cells. | Paclitaxel | ATP binding cassette subfamily B member 1 | Homo sapiens |