Title : Caloric restriction causes secretagogue specific changes of gastric acid secretion in rats.

Pub. Date : 1997 Feb 26

PMID : 9100288






3 Functional Relationships(s)
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1 Gastrin treatment (5 micrograms.kg-1.h-1) of CR rats restored the gastric acid responses to both histamine and carbachol. Histamine gastrin Rattus norvegicus
2 These results suggest that CR can selectively decrease the gastric acid responses to both histamine and carbachol by depletion of the endogenous tissue stores of gastrin. Histamine gastrin Rattus norvegicus
3 More importantly, these results indicate that under an in vivo gastrin-diminished condition, histamine is not the final secretagogue for gastric acid secretion. Histamine gastrin Rattus norvegicus