Title : Loss of heterozygosity at the 5,10-methylenetetrahydrofolate reductase locus in human ovarian carcinomas.

Pub. Date : 1997

PMID : 9099956






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The high-affinity folate-binding protein (FBP) is primarily involved in the uptake of the 5-methyltetrahydrofolate, and its expression may be physiologically regulated by the intracellular folate content. Folic Acid folate receptor beta Homo sapiens
2 The overexpression of FBP on the cell surface of ovarian carcinoma cells may be responsible for an increased folate uptake. Folic Acid folate receptor beta Homo sapiens