Pub. Date : 1997 Apr 18
PMID : 9099734
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tyrosine phosphorylation of the related adhesion focal tyrosine kinase in megakaryocytes upon stem cell factor and phorbol myristate acetate stimulation and its association with paxillin. | Tetradecanoylphorbol Acetate | protein tyrosine kinase 2 beta | Homo sapiens |
| 2 | Stem cell factor, which potentiates the growth of megakaryocytes and their progenitors, and phorbol myristate acetate, which causes differentiation of megakaryocytic cell lines, induced the tyrosine phosphorylation of RAFTK but not of focal adhesion kinase. | Tetradecanoylphorbol Acetate | protein tyrosine kinase 2 beta | Homo sapiens |
| 3 | Cytochalasin D, which disrupts the cytoskeleton, abolished the phosphorylation of RAFTK upon phorbol myristate acetate and stem cell factor stimulation, indicating that RAFTK association with the actin cytoskeleton appears to be critical for its phosphorylation. | Tetradecanoylphorbol Acetate | protein tyrosine kinase 2 beta | Homo sapiens |
| 4 | Cytochalasin D, which disrupts the cytoskeleton, abolished the phosphorylation of RAFTK upon phorbol myristate acetate and stem cell factor stimulation, indicating that RAFTK association with the actin cytoskeleton appears to be critical for its phosphorylation. | Tetradecanoylphorbol Acetate | protein tyrosine kinase 2 beta | Homo sapiens |
| 5 | Transient overexpression of a dominant-negative mutant of RAFTK inhibited significantly the tyrosine phosphorylation of paxillin upon phorbol myristate acetate stimulation. | Tetradecanoylphorbol Acetate | protein tyrosine kinase 2 beta | Homo sapiens |