Title : Activation and dimerization of type III nitric oxide synthase by submicromolar concentrations of tetrahydrobiopterin in microsomal preparations from human primordial placenta.

Pub. Date : 1997 Mar-Apr

PMID : 9089781






2 Functional Relationships(s)
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1 Thirdly, immunoblot analysis combined with laser densitometric evaluation demonstrated that BH4 efficiently promoted the aggregation of microsomal NOS type III isozyme into a protein having the characteristics (electrophoretic mobility, resistance of SDS) of the dimeric form. sapropterin nitric oxide synthase 3 Homo sapiens
2 This is the first time that BH4-induced dimerization of a NOS type III isoform has been demonstrated. sapropterin nitric oxide synthase 3 Homo sapiens