Title : Inhibition of lactate export by quercetin acidifies rat glial cells in vitro.

Pub. Date : 1997 Feb 21

PMID : 9089688






5 Functional Relationships(s)
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1 The relationship between glial lactate release and glial intracellular pH (pHi) regulation is studied using C6 glioma cells and rat astrocytes in vitro, and the lactate transport inhibitors quercetin and alpha-cyano-4-hydroxycinnamate (CHC). Lactic Acid glucose-6-phosphate isomerase Rattus norvegicus
2 A participation of quercetin-inhibitable lactate transport in glial pHi-regulation is suggested by the observation that pHi-homeostasis after acidification by diffusion of undissociated lactic acid into the cell is inhibited by quercetin. Lactic Acid glucose-6-phosphate isomerase Rattus norvegicus
3 A participation of quercetin-inhibitable lactate transport in glial pHi-regulation is suggested by the observation that pHi-homeostasis after acidification by diffusion of undissociated lactic acid into the cell is inhibited by quercetin. Lactic Acid glucose-6-phosphate isomerase Rattus norvegicus
4 A participation of quercetin-inhibitable lactate transport in glial pHi-regulation is suggested by the observation that pHi-homeostasis after acidification by diffusion of undissociated lactic acid into the cell is inhibited by quercetin. Lactic Acid glucose-6-phosphate isomerase Rattus norvegicus
5 A participation of quercetin-inhibitable lactate transport in glial pHi-regulation is suggested by the observation that pHi-homeostasis after acidification by diffusion of undissociated lactic acid into the cell is inhibited by quercetin. Lactic Acid glucose-6-phosphate isomerase Rattus norvegicus