Title : Tyrosine phosphorylation and Syk activation are involved in thrombin-induced aggregation of epinephrine-potentiated platelets.

Pub. Date : 1997 Feb

PMID : 9089407






2 Functional Relationships(s)
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1 Tyrosine phosphorylation and Syk activation are involved in thrombin-induced aggregation of epinephrine-potentiated platelets. Epinephrine coagulation factor II, thrombin Homo sapiens
2 Although epinephrine alone (4 microM) slightly induced protein-tyrosine phosphorylation and Syk activation, the presence of epinephrine caused a shift to the left in the dose-dependence of thrombin (0.01-0.5 U/ml)-induced tyrosine phosphorylation and Syk activation, as well as platelet aggregation. Epinephrine coagulation factor II, thrombin Homo sapiens