Title : Enhancement by vasopressin of adrenergic responses in human mesenteric arteries.

Pub. Date : 1997 Mar

PMID : 9087579






2 Functional Relationships(s)
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1 The aim of the present study was to investigate whether subpressor concentrations of vasopressin could modify the constrictor responses to norepinephrine and electrical stimulation of the perivascular nerves in human mesenteric arteries. Norepinephrine arginine vasopressin Homo sapiens
2 Vasopressin (3 x 10(-11) M) enhanced the contractions elicited by electrical stimulation at 2, 4, and 8 Hz (by 100, 100, and 72%, respectively) and produced a leftward shift of the concentration-response curves to norepinephrine (half-maximal effective concentration decreased from 2.2 x 10(-6) to 5.0 x 10(-7) M; P < 0.05) without any alteration in maximal contractions. Norepinephrine arginine vasopressin Homo sapiens