Title : Imipramine demethylation in vivo: impact of CYP1A2, CYP2C19, and CYP3A4.

Pub. Date : 1997 Mar

PMID : 9084457






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Imipramine demethylation in vivo: impact of CYP1A2, CYP2C19, and CYP3A4. Imipramine cytochrome P450 family 1 subfamily A member 2 Homo sapiens
2 At least three different P450s appear to be responsible for the N-demethylation of imipramine to desipramine in vivo: CYP1A2, CYP2C19, and CYP3A4. Imipramine cytochrome P450 family 1 subfamily A member 2 Homo sapiens