Title : Mesangial cell proliferation mediated by PDGF and bFGF is determined by levels of the cyclin kinase inhibitor p27Kip1.

Pub. Date : 1997 Apr

PMID : 9083274






1 Functional Relationships(s)
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1 Reducing the levels of p27 resulted in an increased magnitude of mesangial cell proliferation (BrdU and 3H-thymidine incorporation) induced by PDGF and bFGF compared to non-transfected mesangial cells and mesangial cells transfected with control mismatch oligodeoxynucleotides. Tritium fibroblast growth factor 2 Rattus norvegicus