Pub. Date : 1997 Apr
PMID : 9083266
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | At 10 to 20 microM, LPA stimulated thymidine incorporation as well as phosphorylation of mitogen-activated protein kinases (MAP-kinases) p42-p44 in dose- and time-dependent manner, which demonstrated a positive effect on cell proliferation. | lysophosphatidic acid | mitogen activated protein kinase 3 | Rattus norvegicus |
| 2 | However, higher concentrations of LPA (100 microM) were unable to stimulate thymidine incorporation and partly inhibited the proliferative effect as well as p42-p44 phosphorylation evoked by serum. | lysophosphatidic acid | mitogen activated protein kinase 3 | Rattus norvegicus |