Title : Modulation of P-glycoprotein mediated drug accumulation in multidrug resistant CCRF VCR-1000 cells by chemosensitisers.

Pub. Date : 1996 May

PMID : 9081366






2 Functional Relationships(s)
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1 Therefore, we compared the effects of five potent chemosensitisers on cellular accumulation using [3H]daunomycin, [3H]vincristine and rhodamine-123 as substrates for PGP. Rhodamine 123 ATP binding cassette subfamily B member 1 Homo sapiens
2 Our data point to similar, if not identical, mechanisms of drug transport by PGP and inhibition of drug transport by chemosensitisers at least for the substrates rhodamine-123, vincristine and daunomycin. Rhodamine 123 ATP binding cassette subfamily B member 1 Homo sapiens