Title : Isolation of a new mouse 3beta-hydroxysteroid dehydrogenase isoform, 3beta-HSD VI, expressed during early pregnancy.

Pub. Date : 1997 Apr

PMID : 9075693






1 Functional Relationships(s)
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1 The demonstration that mouse 3beta-HSD VI functions as a dehydrogenase/isomerase and is the predominant isoform expressed during the first half of pregnancy in uterine tissue and in embryonic cells suggests that this isoform may be involved in local production of progesterone, which is needed for successful implantation of the blastocyst and/or maintenance of early pregnancy. Progesterone hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 Mus musculus