Title : Structure and function of fibroblast growth factor.

Pub. Date : 1996 Jul

PMID : 9070372






1 Functional Relationships(s)
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1 Based on the reported studies, we propose some important requirements of an oligosaccharide to potentiate FGF-1 mitogenic activity: 1) to have a minimum of twelve units, organized as disaccharides where one of the units is a uronic acid and the second is glycosamine; 2) to have at least one iduronic acid sulfated at position 2 and 3) to have N-sulfated glycosamines, preferentially 6-O-sulfated. Uronic Acids fibroblast growth factor 1 Homo sapiens