Pub. Date : 1997 Feb
PMID : 9068340
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Halothane and PMA in combination reduced membrane PKC activity to undetectable levels and reduced cytosol PKC activity (P < 0.01). | Tetradecanoylphorbol Acetate | protein kinase C, alpha | Rattus norvegicus |
| 2 | Halothane and PMA in combination reduced membrane PKC activity to undetectable levels and reduced cytosol PKC activity (P < 0.01). | Tetradecanoylphorbol Acetate | protein kinase C, alpha | Rattus norvegicus |
| 3 | Experiments using isoform-selective antibodies to PKC alpha, PKC beta or PKC gamma demonstrated synergistic interactions between halothane and PMA in promoting translocation of the three conventional PKC isoforms from the cytosol to the membrane fraction of synaptosomes and down-regulation of their immunoreactivity. | Tetradecanoylphorbol Acetate | protein kinase C, alpha | Rattus norvegicus |
| 4 | Experiments using isoform-selective antibodies to PKC alpha, PKC beta or PKC gamma demonstrated synergistic interactions between halothane and PMA in promoting translocation of the three conventional PKC isoforms from the cytosol to the membrane fraction of synaptosomes and down-regulation of their immunoreactivity. | Tetradecanoylphorbol Acetate | protein kinase C, alpha | Rattus norvegicus |
| 5 | Halothane and PMA together reduced cytosol PKC alpha/beta/gamma immunoreactivity significantly more (P < 0.05) than PMA alone. | Tetradecanoylphorbol Acetate | protein kinase C, alpha | Rattus norvegicus |