Pub. Date : 1997 Feb
PMID : 9063478
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The gene transfectant with gamma-glutamylcysteine synthetase (gamma-GCS) gene, a rate limiting enzyme in GSH biosynthesis, exerted increased GSH content and ATP-dependent glutathione S-conjugate export pump (GS-X pump) decreased intracellular platinum and sensitivity against cisplatin. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 2 | It is suggested that GS-X pump expression is related to cellular GSH metabolism and involved in cisplatin resistance. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |