Title : Neuroprotective action of cycloheximide involves induction of bcl-2 and antioxidant pathways.

Pub. Date : 1997 Mar 10

PMID : 9060477






1 Functional Relationships(s)
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1 Neuroprotective concentrations of CHX caused only a moderate (20-40%) reduction in overall protein synthesis, and induced an increase in c-fos, c-jun, and bcl-2 mRNAs and protein levels as determined by reverse transcription-PCR analysis and immunocytochemistry, respectively. Cycloheximide Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus