Title : Blockage of 5HT2C serotonin receptors by fluoxetine (Prozac).

Pub. Date : 1997 Mar 4

PMID : 9050900






1 Functional Relationships(s)
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1 In accord with the electrophysiological results, fluoxetine inhibited the binding of [3H]5HT to 5HT2C receptors expressed in HeLa cells (Ki approximately 65-97 nM), and the binding to 5HT receptors in rat cortex membranes was also inhibited but less efficiently (Ki approximately 56 microM). Tritium 5-hydroxytryptamine receptor 2C Homo sapiens