Title : Increased gadd153 messenger RNA level is associated with apoptosis in human leukemic cells treated with etoposide.

Pub. Date : 1997 Feb 15

PMID : 9044846






1 Functional Relationships(s)
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1 Both gadd153 mRNA level increase and internucleosomal DNA fragmentation were inhibited by N-tosyl-L-phenylalanine chloromethylketone, a serine threonine protease inhibitor, N-acetyl-leucyl-leucyl-norleucinal, an inhibitor of calpain, N-acetylcysteine, an inhibitor of oxidative metabolism, and overexpression of Bcl-2. Tosylphenylalanyl Chloromethyl Ketone BCL2 apoptosis regulator Homo sapiens