Title : The vav proto-oncogene product (p95vav) interacts with the Tyk-2 protein tyrosine kinase.

Pub. Date : 1997 Feb 10

PMID : 9038355






2 Functional Relationships(s)
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1 During engagement of the type I IFN receptor, p95vav is phosphorylated on tyrosine residues, but the kinase regulating its phosphorylation has not been identified to date. Tyrosine interferon alpha 1 Homo sapiens
2 Our studies demonstrate that p95vav forms a stable complex with the IFN-receptor-associated Tyk-2 kinase in vivo, and strongly suggest that this kinase regulates its phosphorylation on tyrosine. Tyrosine interferon alpha 1 Homo sapiens