Title : Inhibition of CPP32-like proteases prevents granzyme B- and Fas-, but not granzyme A-based cytotoxicity exerted by CTL clones.

Pub. Date : 1997 Mar 1

PMID : 9036942






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 N-acetyl-Asp-Glu-Val-Asp aldehyde (Ac-DEVD-CHO), a specific inhibitor of CPP32-like proteases, completely prevented the former type of lysis in 3-h assays, but not in long-term (16-h) assays. acetyl-aspartyl-glutamyl-valyl-aspartal caspase 3 Mus musculus
2 N-acetyl-Asp-Glu-Val-Asp aldehyde (Ac-DEVD-CHO), a specific inhibitor of CPP32-like proteases, completely prevented the former type of lysis in 3-h assays, but not in long-term (16-h) assays. acetyl-aspartyl-glutamyl-valyl-aspartal caspase 3 Mus musculus