Pub. Date : 1997 Feb 1
PMID : 9032461
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The phospholipase A2 (PLA2)-catalysed hydrolysis of phosphatidic acid (PA) is thought to be a primary synthetic route for LPA. | lysophosphatidic acid | phospholipase A2 group IB | Homo sapiens |
| 2 | The phospholipase A2 (PLA2)-catalysed hydrolysis of phosphatidic acid (PA) is thought to be a primary synthetic route for LPA. | lysophosphatidic acid | phospholipase A2 group IB | Homo sapiens |
| 3 | Of the multiple forms of PLA2 present in human tissues, human secretory class-II PLA2 (hs-PLA2) has been implicated in the production of LPA from platelets and whole blood cells challenged with inflammatory stimuli. | lysophosphatidic acid | phospholipase A2 group IB | Homo sapiens |
| 4 | Of the multiple forms of PLA2 present in human tissues, human secretory class-II PLA2 (hs-PLA2) has been implicated in the production of LPA from platelets and whole blood cells challenged with inflammatory stimuli. | lysophosphatidic acid | phospholipase A2 group IB | Homo sapiens |
| 5 | Of the multiple forms of PLA2 present in human tissues, human secretory class-II PLA2 (hs-PLA2) has been implicated in the production of LPA from platelets and whole blood cells challenged with inflammatory stimuli. | lysophosphatidic acid | phospholipase A2 group IB | Homo sapiens |
| 6 | To explore further the possibility that hs-PLA2 is involved in the production of LPA, we rigorously measured the phospholipid head group specificity of hs-PLA2 by a novel PLA2 kinetic system using polymerized mixed liposomes. | lysophosphatidic acid | phospholipase A2 group IB | Homo sapiens |
| 7 | To explore further the possibility that hs-PLA2 is involved in the production of LPA, we rigorously measured the phospholipid head group specificity of hs-PLA2 by a novel PLA2 kinetic system using polymerized mixed liposomes. | lysophosphatidic acid | phospholipase A2 group IB | Homo sapiens |
| 8 | In conjunction with a recent cell study [Fourcade, Simon, Viode, Rugani, Leballe, Ragab, Fournie, Sarda and Chap (1995) Cell 80, 919-927], these studies suggest that hs-PLA2 can rapidly hydrolyse PA molecules exposed to the outer layer of cell-derived microvesicles and thereby produce LPA. | lysophosphatidic acid | phospholipase A2 group IB | Homo sapiens |