Title : High specificity of human secretory class II phospholipase A2 for phosphatidic acid.

Pub. Date : 1997 Feb 1

PMID : 9032461






5 Functional Relationships(s)
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1 Kinetic analysis of recombinant hs-PLA2 demonstrates that hs-PLA2 strongly prefers PA as substrate over other phospholipids found in the mammalian plasma membrane including phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Phosphatidylcholines phospholipase A2 group IB Homo sapiens
2 Kinetic analysis of recombinant hs-PLA2 demonstrates that hs-PLA2 strongly prefers PA as substrate over other phospholipids found in the mammalian plasma membrane including phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Phosphatidylcholines phospholipase A2 group IB Homo sapiens
3 Kinetic analysis of recombinant hs-PLA2 demonstrates that hs-PLA2 strongly prefers PA as substrate over other phospholipids found in the mammalian plasma membrane including phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Phosphatidylcholines phospholipase A2 group IB Homo sapiens
4 Kinetic analysis of recombinant hs-PLA2 demonstrates that hs-PLA2 strongly prefers PA as substrate over other phospholipids found in the mammalian plasma membrane including phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Phosphatidylcholines phospholipase A2 group IB Homo sapiens
5 Thus it appears that Lys-69 is at least partially involved in the PA specificity of hs-PLA2 and Glu-56 in the distinction between PE and PC. Phosphatidylcholines phospholipase A2 group IB Homo sapiens