Title : Effect of pindolol on hormone secretion and body temperature: partial agonist effects.

Pub. Date : 1996

PMID : 9026379






4 Functional Relationships(s)
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1 Pindolol has been shown to be a partial agonist at 5-HT1A receptors in preclinical studies. Pindolol 5-hydroxytryptamine receptor 1A Homo sapiens
2 The increase in plasma cortisol due to pindolol suggests a 5-HT1A agonist action and is consistent with a 5-HT1A partial agonist mechanism in man whereas the PRL effects are consistent with an antagonist action at 5-HT1A receptors. Pindolol 5-hydroxytryptamine receptor 1A Homo sapiens
3 The increase in plasma cortisol due to pindolol suggests a 5-HT1A agonist action and is consistent with a 5-HT1A partial agonist mechanism in man whereas the PRL effects are consistent with an antagonist action at 5-HT1A receptors. Pindolol 5-hydroxytryptamine receptor 1A Homo sapiens
4 The increase in plasma cortisol due to pindolol suggests a 5-HT1A agonist action and is consistent with a 5-HT1A partial agonist mechanism in man whereas the PRL effects are consistent with an antagonist action at 5-HT1A receptors. Pindolol 5-hydroxytryptamine receptor 1A Homo sapiens