Title : Central vasopressin is required for the complete development of deoxycorticosterone-salt hypertension in rats with hereditary diabetes insipidus.

Pub. Date : 1997 Jan 12

PMID : 9021647






6 Functional Relationships(s)
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1 It has been shown that vasopressin receptors are upregulated in the brain and that the central vasopressin pathway is involved in the development of deoxycorticosterone acetate (DOCA)-salt hypertension. Desoxycorticosterone Acetate arginine vasopressin Rattus norvegicus
2 It has been shown that vasopressin receptors are upregulated in the brain and that the central vasopressin pathway is involved in the development of deoxycorticosterone acetate (DOCA)-salt hypertension. Desoxycorticosterone Acetate arginine vasopressin Rattus norvegicus
3 It has been shown that vasopressin receptors are upregulated in the brain and that the central vasopressin pathway is involved in the development of deoxycorticosterone acetate (DOCA)-salt hypertension. Desoxycorticosterone Acetate arginine vasopressin Rattus norvegicus
4 It has been shown that vasopressin receptors are upregulated in the brain and that the central vasopressin pathway is involved in the development of deoxycorticosterone acetate (DOCA)-salt hypertension. Desoxycorticosterone Acetate arginine vasopressin Rattus norvegicus
5 To clarify this issue, the effect of centrally administered vasopressin on the development of DOCA-salt hypertension was studied in homozygous Brattleboro rats which genetically lack vasopressin. Desoxycorticosterone Acetate arginine vasopressin Rattus norvegicus
6 These results suggest that central vasopressin is required for the complete development of DOCA-salt hypertension and the mechanism is, in part, due to enhanced sodium intake through the additive effect of central vasopressin and DOCA-salt. Desoxycorticosterone Acetate arginine vasopressin Rattus norvegicus