Title : A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interaction.

Pub. Date : 1997 Feb 14

PMID : 9020151






2 Functional Relationships(s)
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1 NO-related species stimulated guanine nucleotide exchange on wild-type p21(ras), resulting in an active form, but not on p21(ras)C118S. Guanine Nucleotides H3 histone pseudogene 16 Homo sapiens
2 These data indicate that Cys118 is a critical site of redox regulation of p21(ras), and S-nitrosylation of this residue triggers guanine nucleotide exchange and downstream signaling. Guanine Nucleotides H3 histone pseudogene 16 Homo sapiens