Title : Distinct biological properties of two RET isoforms activated by MEN 2A and MEN 2B mutations.

Pub. Date : 1997 Jan 23

PMID : 9018112






2 Functional Relationships(s)
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1 In this study, we have introduced a MEN 2A mutation (Cys634-->Arg) and the unique MEN 2B mutation (Met918-->Thr) in two RET isoforms of 1114 and 1072 amino acids which differ in the carboxy-terminus part. Threonine ret proto-oncogene Homo sapiens
2 In this study, we have introduced a MEN 2A mutation (Cys634-->Arg) and the unique MEN 2B mutation (Met918-->Thr) in two RET isoforms of 1114 and 1072 amino acids which differ in the carboxy-terminus part. Threonine ret proto-oncogene Homo sapiens