Pub. Date : 1997
PMID : 9013123
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Puromycin aminonucleoside (PAN) toxicity was totally inhibited in the rat in vivo and in cultured glomerular epithelial cells (GECs) in vitro using the adenosine deaminase (ADA) inhibitor, 2"-deoxycoformycin (DCF). | Pentostatin | adenosine deaminase | Rattus norvegicus |
| 2 | Puromycin aminonucleoside (PAN) toxicity was totally inhibited in the rat in vivo and in cultured glomerular epithelial cells (GECs) in vitro using the adenosine deaminase (ADA) inhibitor, 2"-deoxycoformycin (DCF). | Pentostatin | adenosine deaminase | Rattus norvegicus |
| 3 | DCF completely inhibited ADA activity in glomeruli and protected against the development of PAN nephrosis; the 24-h urinary protein excretion of treated rats compared with controls (PAN rats) 9 days after PAN injection was 16 +/- 2 mg and 524 +/- 55 mg, respectively (p < .01). | Pentostatin | adenosine deaminase | Rattus norvegicus |