Title : The different RET-activating capability of mutations of cysteine 620 or cysteine 634 correlates with the multiple endocrine neoplasia type 2 disease phenotype.

Pub. Date : 1997 Feb 1

PMID : 9012462






1 Functional Relationships(s)
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1 We have reported previously that mutations of Cys-634 constitutively activate the RET transforming potential by causing a disulfide bridge-mediated homodimerization. Disulfides ret proto-oncogene Homo sapiens