Title : Cytotoxic effect of autocrine and macrophage-derived nitric oxide on cultured rat mesangial cells.

Pub. Date : 1997 Jan

PMID : 9010260






1 Functional Relationships(s)
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1 Stimulation of MC with IL-1beta and TNF-alpha caused remarkable toxicity to these cells, measured by the MTT test (3-(4,5-dimethylthiazol-2-yl)2,5-diphenyl tetrazolium bromide cleavage, specific cytotoxicity 41.5 +/- 20.3%), and much less prominent MC lysis (3H-thymidine release, specific cytolysis 11.5 +/- 5.3%). thiazolyl blue tumor necrosis factor Rattus norvegicus