Title : Monoclonal antibodies specific for underphosphorylated retinoblastoma protein identify a cell cycle regulated phosphorylation site targeted by CDKs.

Pub. Date : 1997 Jan 16

PMID : 9010227






1 Functional Relationships(s)
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1 We provide evidence that this residue, serine 608 of pRB, is an authentic phosphorylation site that can be phosphorylated in vitro by cyclin A-CDK2 and cyclin D1-CDK4 kinases but not by cyclin E-CDK2 kinase or the mitogen activated kinase ERK2. Serine mitogen-activated protein kinase 1 Homo sapiens