Title : Effects found in a one-year oral toxicity study in Sprague-Dawley rats of a novel 5-HT1A receptor partial agonist for the treatment of anxiety in humans.

Pub. Date : 1996 Mar-Apr

PMID : 8992611






1 Functional Relationships(s)
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1 A potent and selective serotonin (5-HT1A) partial agonist with potential as a human anxiolytic drug was given in oral doses of 0, 5, 15, or 50 mg/kg/day by gavage to Sprague-Dawley rats for 6 or 12 mo. Serotonin 5-hydroxytryptamine receptor 1A Homo sapiens