Title : Phenacetin O-deethylation by human liver microsomes in vitro: inhibition by chemical probes, SSRI antidepressants, nefazodone and venlafaxine.

Pub. Date : 1996 Dec

PMID : 8986010






1 Functional Relationships(s)
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1 Biotransformation of phenacetin via O-deethylation to acetaminophen, an index reaction reflecting activity of Cytochrome P450-1A2, was studied in microsomal preparations from a series of human livers. Phenacetin cytochrome P450 family 1 subfamily A member 2 Homo sapiens