Pub. Date : 1997 Jan
PMID : 8981358
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, enforced expression of c-myc or D-type cyclins, but not cyclin E, resensitizes cells bearing CSF-1R (Y809F) to the mitogenic effects of CSF-1, enabling them to proliferate continuously in liquid culture and to form colonies in agar in response to the growth factor. | Agar | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | Conversely, cyclin D1-rescued cells were inhibited from forming CSF-1-dependent colonies in agar when challenged with either a dominant-negative c-myc mutant or mad, a transcription factor which competes with myc for max, its requisite heterodimeric partner. | Agar | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |