Title : Topical azelastine reduces eosinophil activation and intercellular adhesion molecule-1 expression on nasal epithelial cells: an antiallergic activity.

Pub. Date : 1996 Dec

PMID : 8977510






3 Functional Relationships(s)
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1 Topical azelastine reduces eosinophil activation and intercellular adhesion molecule-1 expression on nasal epithelial cells: an antiallergic activity. azelastine intercellular adhesion molecule 1 Homo sapiens
2 After azelastine administration, significant decreases in total symptom score, eosinophilic and neutrophilic infiltration, and ICAM-1 expression were observed during both early- and late-phase reactions. azelastine intercellular adhesion molecule 1 Homo sapiens
3 CONCLUSION: Azelastine exerts antiallergic activity, mainly affecting eosinophil function and downregulating ICAM-1 expression, on nasal epithelial cells. azelastine intercellular adhesion molecule 1 Homo sapiens