Pub. Date : 1996 Dec
PMID : 8977508
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Peripheral blood mononuclear cell GCR binding affinities for dexamethasone and budesonide were also determined for both patient groups by using a radioligand binding assay and Scatchard analysis. | Budesonide | nuclear receptor subfamily 3 group C member 1 | Homo sapiens |
| 2 | The GCR binding affinity for budesonide was significantly higher in both groups (i.e., lower dissociation constant) than that obtained for dexamethasone. | Budesonide | nuclear receptor subfamily 3 group C member 1 | Homo sapiens |
| 3 | CONCLUSION: These data suggest that glucocorticoids such as budesonide, by virtue of their high GCR binding affinities and greater ability to suppress lymphocyte proliferation, may therefore be beneficial in the management of difficult-to-control asthma. | Budesonide | nuclear receptor subfamily 3 group C member 1 | Homo sapiens |