Title : Cadmium affects the activity of rat liver tyrosine aminotransferase and its induction by dexamethasone.

Pub. Date : 1996

PMID : 8975639






2 Functional Relationships(s)
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1 The effects of cadmium (Cd) administration to intact rats on hepatic glucocorticoid receptor (GR) steroid binding capacity and DNA-binding ability were examined and correlated with the influence of the metal on rat liver tyrosine aminotransferase (TAT) activity and its induction by dexamethasone. Steroids nuclear receptor subfamily 3, group C, member 1 Rattus norvegicus
2 administration of Cd doses ranging from 0.5 to 4 mg/kg, the GR steroid- and DNA-binding activities were significantly reduced in a dose-dependent manner. Steroids nuclear receptor subfamily 3, group C, member 1 Rattus norvegicus