Pub. Date : 1996 May
PMID : 8967457
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Delta F508-CFTR channels: kinetics, activation by forskolin, and potentiation by xanthines. | Colforsin | cystic fibrosis transmembrane conductance regulator | Mus musculus |
| 2 | Western blots detected a small amount of fully glycosylated delta F508-CFTR Efflux of 125I was stimulated by forskolin with the same mean effective concentration (EC50; approximately 0.5 microM) for CFTR and delta F508-CFTR cells, but the maximum response was reduced more than fivefold and its latency increased approximately threefold in delta F508-CFTR cells. | Colforsin | cystic fibrosis transmembrane conductance regulator | Mus musculus |
| 3 | Single-channel currents were detected in 57 of 68 cell-attached patches from forskolin-prestimulated CFTR cells vs. 6 of 35 patches in delta F508-CFTR cells. | Colforsin | cystic fibrosis transmembrane conductance regulator | Mus musculus |
| 4 | We estimate that forskolin-stimulated chloride conductance of delta F508-CFTR C127I cells is < 5% of CFTR cells. | Colforsin | cystic fibrosis transmembrane conductance regulator | Mus musculus |
| 5 | We estimate that forskolin-stimulated chloride conductance of delta F508-CFTR C127I cells is < 5% of CFTR cells. | Colforsin | cystic fibrosis transmembrane conductance regulator | Mus musculus |