Pub. Date : 1995 Dec
PMID : 8963479
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tight binding of ramiprilat to ACE: consequences for pharmacokinetic and pharmacodynamic measurements. | ramiprilat | angiotensin I converting enzyme | Homo sapiens |
| 2 | The present paper discusses how tight binding of ramiprilat to ACE affects the pharmacokinetic characteristics and in vitro measurement of ACE inhibition. | ramiprilat | angiotensin I converting enzyme | Homo sapiens |
| 3 | The present paper discusses how tight binding of ramiprilat to ACE affects the pharmacokinetic characteristics and in vitro measurement of ACE inhibition. | ramiprilat | angiotensin I converting enzyme | Homo sapiens |
| 4 | With respect to pharmacodynamics, free ramiprilat depletion due to tight binding is the reason for the steep nature of concentration-effect curves often observed for ACE inhibition. | ramiprilat | angiotensin I converting enzyme | Homo sapiens |