Title : Effect of bolus milrinone on hemodynamic variables and pulmonary vascular resistance in patients with severe left ventricular dysfunction: a rapid test for reversibility of pulmonary hypertension.

Pub. Date : 1996 Dec

PMID : 8962566






5 Functional Relationships(s)
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1 OBJECTIVES: To examine the feasibility of using milrinone to test pulmonary vascular reactivity in patients before heart transplantation, we tested the hypothesis that milrinone would lower pulmonary vascular resistance (PVR) in patients with severe heart failure. Milrinone PVR cell adhesion molecule Homo sapiens
2 The ability of milrinone to lower PVR in patients with heart failure has not been tested. Milrinone PVR cell adhesion molecule Homo sapiens
3 RESULTS: Milrinone decreased PVR in all patients. Milrinone PVR cell adhesion molecule Homo sapiens
4 The magnitude of the decrease in PVR correlated inversely with the milrinone-induced increase in cardiac output. Milrinone PVR cell adhesion molecule Homo sapiens
5 CONCLUSIONS: Bolus milrinone consistently decreases PVR in patients with pulmonary hypertension secondary to severe heart failure. Milrinone PVR cell adhesion molecule Homo sapiens