Pub. Date : 1996 Dec 10
PMID : 8961946
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Refolding of thermally and urea-denatured ribonuclease A monitored by time-resolved FTIR spectroscopy. | Urea | ribonuclease A family member 1, pancreatic | Homo sapiens |
| 2 | Therefore, our kinetic infrared studies provide evidence for a high structural similarity of urea-denatured and heat-denatured RNase A, corroborating the conclusions derived from the direct comparison of the infrared spectra of thermally and chemically denatured RNase A under equilibrium conditions [Fabian, H., & Mantsch, H.H. | Urea | ribonuclease A family member 1, pancreatic | Homo sapiens |
| 3 | In detail, the kinetic infrared data demonstrate that in the time window of 0.1-30 s approximately 40% of the native beta-sheet structure in RNase A is formed in the presence of 0.6 M urea at pH* 3.6, indicating that up to 60% of the beta-structure is formed out of the time window used in this study. | Urea | ribonuclease A family member 1, pancreatic | Homo sapiens |